WebFeb 6, 2024 · โซลิเฟนาซิน (Solifenacin) คือ ยาประเภทแอนตี้มัสคารินิก (Antimuscarinic) ถูกพัฒนา ขึ้นเพื่อใช้รักษาอาการกระเพาะปัสสาวะไวเกิน (Over active urinary bladder) จนมีอาการกลั้นปัสสาวะ ... WebThe aim of the randomised, double blind, placebo controlled study was to evaluate the efficacy, tolerability and safety of solifenacin, a once-daily M3 selective receptor antagonist, in patients with overactive bladder syndrome. Following a single blind 2-week placebo run in period, patients who com …
The efficacy and safety of solifenacin in patients with ... - PubMed
WebSolifenacin afhjælper lagringsfunktionsproblemer relateret til aktivering af M3-receptorer i blæren forårsaget af ikke-neuronalt frigivet acetylkolin. Ikke-neuronalt frigivet acetylkolin sensibiliserer sensorisk urotelfunktion og manifesteres som imperiøs vandladning og vandladningshyppighed. WebFor solifenacin succinate. Manufacturer advises for oral suspension, doses should be followed by a glass of water—ingestion with food or other drinks may lead to the release … coved cernay
Solifenacin 5 mg film-coated tablets - Summary of Product ...
WebNov 27, 2024 · Expert advice for Solifenacin. Solifenacin helps you to have better control over your urination by relaxing your bladder which increases its capacity to hold urine, thereby reducing the need to pass urine. It may cause blurred vision, fatigue and sleepiness. Be cautious while driving or doing anything that requires focus. WebOct 1, 2006 · Solifenacin reduced daily micturitions by 2.45 compared to a reduction of 2.24 with tolterodine. Incontinence episodes per 24 hours reduced by a mean of 1.6 with … Solifenacin, sold as the brand name Vesicare among others, is a medicine used to treat overactive bladder and neurogenic detrusor overactivity (NDO). It may help with incontinence, urinary frequency, and urinary urgency. Benefits appear similar to other medications in the class. It is taken by mouth. Common side … See more It is used to treat overactive bladder. It may help with incontinence, urinary frequency, and urinary urgency. Benefits appear similar to other antimuscarinics such as oxybutynin, tolterodine, … See more The most common side effects of solifenacin are dry mouth, constipation and urinary tract infection. As all anticholinergics, … See more Mechanism of action Solifenacin is a competitive cholinergic receptor antagonist, selective for the M3 receptor subtype. The binding of acetylcholine to these receptors, particularly M3, plays a critical role in the contraction of See more The compound was studied using animal models by the Yamanouchi Pharmaceutical Co., Ltd. of Tokyo, Japan. It was known as YM905 when under study in the early 2000s. See more Solifenacin is contraindicated for people with urinary retention, gastric retention, uncontrolled or poorly controlled closed-angle glaucoma, severe liver disease (Child-Pugh class … See more Solifenacin is metabolized in the liver by the cytochrome P450 enzyme CYP3A4. When administered concomitantly with drugs that See more Like other anticholinergics, solifenacin is an ester of a carboxylic acid containing (at least) an aromatic ring with an alcohol containing a … See more coved ceramic tile