Hif 1 alpha uniprot

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August undefined, 2024

Web2 de fev. de 2024 · The enrichment pathways identified following KEGG analysis that contained the most core targets (p < 0.05) included cocaine addiction, calcium signaling pathway, arginine biosynthesis, HIF-1 signaling pathway, pathways of neurodegeneration-multiple diseases, estrogen signaling pathway, chemical carcinogenesis-receptor … WebProduct Specific Information. MA1-516 detects hypoxia-inducible factor 1 alpha (HIF-1 alpha) from human, non-human primate, bovine, mouse and porcine cells. This antibody does not cross-react with ARNT or the related HIF-2 alpha. MA1-516 has been successfully used in Western blot, immunofluorescence, immunoprecipitation, immunocytochemistry ...

RAR相关孤儿受体 - 维基百科，自由的百科全书

Web3 de jul. de 2003 · Hypoxia-inducible factor 2-alpha (HIF-2-alpha; HIF2-alpha) Member of PAS protein 2; PAS domain-containing protein 2; Gene names. Name. EPAS1. … WebMonoclonal Anti-HIF2 alpha antibody produced in mouse. clone GT125, affinity isolated ... UniProt accession no. Q16665. shipped in. wet ice. storage temp. −20°C. Gene ... Hif1a(15251) rat ... Hif1a(29560) Description. General description. Hypoxia-inducible factor-1 (HIF-1) is a 120kD basic helix-loop-helix protein that belongs to the PAS ... bistro jolie beverly hills

HIF1A Monoclonal Antibody (mgc3) (MA1-516) - Thermo Fisher …

WebHIF-1-alpha 1 publication; HIF1-alpha 1 publication. Alternative names. ARNT-interacting protein; ... 1-826: UniProt: Hypoxia-inducible factor 1-alpha: BLAST Add. Sequence: Glycosylation: 18: UniProt (Microbial infection) N-beta-linked (GlcNAc) arginine 1 publication. Sequence: R: Modified residue: 247: Web6 de out. de 2024 · HIF is a transcription factor that plays an essential role in the cellular response to low oxygen, orchestrating a metabolic switch that allows cells to survive in this environment. In immunity, infected and inflamed tissues are often hypoxic, and HIF helps immune cells adapt. HIF-α stabilization ca … WebA fusion protein including amino acids 530 - 825 of the mouse HIF-1 alpha protein [UniProt# Q61221]. Purification Purified by antigen-affinity chromatography Conjugation … bistro kettle chips

HIF-1alpha monoclonal antibody Immunohistochemistry, Western ...

HIF-1 and mechanisms of hypoxia sensing - PubMed

Web17 de jan. de 2003 · The activity of the transcription factor hypoxia-inducible factor (HIF) is regulated by oxygen-dependent hydroxylation. Under normoxic conditions, hydroxylation … Web16 de jun. de 2003 · Hydroxylates HIF-1 alpha at 'Asn-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the … bistro kitchen decorationsWebGet better batch-to-batch reproducibility with a recombinant antibody. Anti-HIF-1 alpha antibody [EPR16897] (ab179483) Research with confidence – consistent and reproducible results with every batch. Long-term and scalable supply – powered by recombinant technology for fast production. Success from the first experiment – confirmed ... darts check out theorie

"WebWe investigated the impact of inhibiting HIF-1α transcriptional activity on cytotoxic immune cell infiltration into B16-F10 melanoma. We showed that tumors expressing a deleted form of HIF-1α displayed increased levels of NK and CD8 + effector T cells in the tumor microenvironment, which was associated with high levels of CCL2 and CCL5 ... " - Hif 1 alpha uniprot

Hif 1 alpha uniprot

Mouse HIF-1 alpha ELISA Kit (ab275103) Abcam

WebCell growth and viability is compromised by oxygen deprivation (hypoxia). Hypoxia-inducible factors, including HIF-1α, Arnt 1 (also designated HIF-1β), EPAS-1 (also designated HIF-2α) and HIF-3α, induce glycolysis, erythropoiesis and angiogenesis in … WebCrystal structure of a hydroxylated hif-1 alpha peptide bound to the pvhl/elongin-c/elongin-b complex . Experiment type: X-ray diffraction, resolution 2.00Å Release ... This section shows the Pfam domains which are found on the UniProt sequence(s) referred to by this structure.

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WebRAR相关孤儿受体（英語： RAR-related orphan receptor ， RORs ）是核受体的一个家族，是细胞内转录因子的一员 [1] [2] 。. 有三个ROR家族成员： ROR-α 、 -β 和 -γ 分别由基因 RORA 、 RORB 、 RORC 编码。. RORs的不寻常之处在于它们是以单体形式结合到激素 … WebHuman HIF-1 alpha ELISA kit (ab275103) is a single-wash 90 min sandwich ELISA designed for the quantitative measurement of Human HIF-1 alpha protein in cell and tissue extracts. It uses our proprietary SimpleStep ELISA® technology. Quantitate Human HIF-1 alpha with 33.39 pg/mL sensitivity.

Web19 de set. de 2012 · Identification of Cys 255 in HIF-1 as a novel site for development of covalent inhibitors of HIF-1 /ARNT PasB domain ... Identification of Cys255 in HIF-1 … Web12 de ago. de 2002 · 1H2K, 1H2L, 1H2M, 1H2N. PubMed Abstract: The activity of the transcription factor hypoxia-inducible factor (HIF) is regulated by oxygen-dependent …

Web8 de mai. de 2015 · Crystal Structure of the Heterodimeric HIF-1a:ARNT Complex with HRE DNA. Crystal Structure of the Heterodimeric HIF-1a: ... UniProt & NIH Common Fund … WebImmunocytochemistry analysis of HIF1A in immersion fixed HeLa human cervical epithelial carcinoma cell line treated with DFOA. Samples were incubated in HIF1A monoclonal antibody (Product # MA1-16504) using a dilution of 1 µg/mL followed by donkey anti-rabbit secondary antibody and counterstained with DAPI (blue).

Web結構. 缺氧大部分需要氧氣呼吸的物種，都擁有保守序列HIF-1。其轉錄都有嚴格的調控機制。HIF-1是由一個α亞基和一個β亞基組成的異源蛋白二聚體，而β亞基是一種芳香烃受体核转位子（英语： Aryl hydrocarbon receptor nuclear translocator ）（ARNT）。 HIF-1屬於鹼性螺旋-環-螺旋（bHLH）家族中的PER-ARNT-SIM ...

WebHypoxia-inducible factor 1 (HIF-1) is an oxygen-regulated transcriptional activator that plays essential roles in mammalian development, physiology and disease pathogenesis. The HIF-1 alpha subunit is subjected to oxygen-dependent ubiquitination and proteasomal degradation that is mediated by the vo … bistro kings crossWeb9 de mai. de 2002 · Crystal structure of a hydroxylated HIF-1 alpha peptide bound to the pVHL/elongin-C/elongin-B complex. ... Hypoxia-inducible factor 1 ALPHA: D: 34: N/A: Mutation(s): 1 : UniProt & NIH Common Fund Data Resources: Find proteins for Q16665 (Homo sapiens) Explore Q16665 . Go to UniProtKB: Q16665. PHAROS: Q16665. bistro jersey city njWeb12 de ago. de 2002 · 1H2K, 1H2L, 1H2M, 1H2N. PubMed Abstract: The activity of the transcription factor hypoxia-inducible factor (HIF) is regulated by oxygen-dependent hydroxylation. Under normoxic conditions, … dartscheibe canaveral ed 520WebUniProt website fallback message If you are not seeing anything on this page, it might be for multiple reasons: You might have JavaScript disabled: make sure to ... bistro kibbles and bitsWeb21 de mar. de 2024 · HIF1A (Hypoxia Inducible Factor 1 Subunit Alpha) is a Protein Coding gene. Diseases associated with HIF1A include Retinal Ischemia and Enchondromatosis, Multiple, Ollier Type.Among its related pathways are Signaling by PTK6 and Regulation of activated PAK-2p34 by proteasome mediated degradation.Gene … bistro kitchen nightmaresWeb13 de fev. de 2024 · HIF prolyl hydroxylases are oxygen sensors that regulate the stability of the hypoxia-inducible factors (HIFs) in an oxygen-dependent manner. Aragones et al. (2008) showed that loss of Phd1 expression in knockout mice lowers oxygen consumption in skeletal muscle by reprogramming glucose metabolism from oxidative to more anaerobic … darts chelmsfordWebBackground: HIF-1 alpha/HIF1A. This biotinylated peptide includes a sequence from human Hypoxia-Inducible Factor 1-alpha (HIF-1 alpha ) with an unmodified (non-hydroxylated) proline residue corresponding to proline 564 in UniProt Q16665. The peptide is not efficiently ubiquitinated by a VHL/Elongin B/Elongin C/CUL2/RBX complex (catalog … dartscheibe ally pally